Too Hot? Too Cold? When Is it “Just Right” to Stop Dual Antiplatelet Therapy After PCI With DES?

Not Too Hot, Not Too Cold: The Bundled-SVM is Just Right!

The Support Vector Machine (SVM) typically outperforms other algorithms on text classification problems, but requires training time roughly quadratic in the number of training documents. In contrast, linear time algorithms like Naive Bayes have lower performance, but can easily handle huge training sets. In this paper, we describe a technique that creates a continuum of classifiers between the ...

When is it too late for cardiac resynchronization therapy?

Lehmann et al.1 pointed out that taken together, the large cardiac resynchronization therapy (CRT) trials included 10,803 patients, the majority of who were in congestive heart failure (CHF) New York Heart Association (NYHA) class III, but only 451 patients (4.2%) were class IV. The role of CRT in NYHA class IV patients remained uncertain until recently when Lindenfeld et al.2 reported the resu...

The QT interval: too long, too short or just right.

Four Inches ! Too Close , Too Far , Just Right ?

The July 1992 Indoor Radon and Radon Decay Product Measurement Device Protocols, EPA 402-R-92-004 (EPA 1992) provides five measurement device location selection criteria that should be followed when placing a device within a room for measurement of the radon concentration. These criteria include: (1) a place where the device will not be disturbed and there is adequate room for the device, (2) a...

Considering age when making treatment decisions in the ICU: too little, too much, or just right?

There are a number of studies providing evidence that age is associated with treatment decisions for critically ill adults, although most of these studies have been unable to fully account for both prehospital health status and severity of acute illness. In the previous issue of Critical Care, Turnbull and colleagues present a well-executed study analyzing data from a prospective cohort study o...